Includes index.

Rev. ed. of: Comprehensive pharmacy review / editors, Leon Shargel ... [et al.]. 7th ed. c2010.

Includes bibliographical references and index.

Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.

"This eighth edition of Comprehensive Pharmacy Review reflects the continuing evolution of pharmacy practice and educational requirements. The main objective of the book is to provide a comprehensive study guide for pharmacy students and other candidates who are preparing for the North American Pharmacist Licensure Examination (NAPLEX). This volume represents the contributions of more than 50 specialists who provide wide expertise in pharmaceutical science, pharmacy practice, and clinical pharmacy. Their contributions to Comprehensive Pharmacy Review assure that this review guide is accurate and current as well as written in a comprehensible manner for students, teachers, and practitioners alike. This review publication, along with the separate booklet of simulated NAPLEX exams (Comprehensive Pharmacy Review Practice Exams, 8th edition), provides both guidance and test practice for NAPLEX candidates"--Provided by publisher.